Begrenset erfaring med bruk hos gravide. Som for benzodiazepiner kan ikke uheldige virkninger på fosteret eller det nyfødte barn utelukkes
Zopiclone is extensively and speedily metabolised via the liver. Numerous metabolites are already isolated and characterised, Using the two important ones getting the N-oxide, produced by oxidation of your piperazine nitrogen along with the N-desmethyl produced by oxidative demethylation with the N-methyl piperazine. Only the N-oxide analogue has weak pharmacological action.
Nedsatt konsentrasjon av zopiklon. Basert på facts fra andre kraftige induktorer av CYP3A4 må person regne med at konsentrasjonen av zopiklon kan synke med i størrelsesorden inntil eighty %.
Imovane innehåller den aktiva substansen zopiklon som påverkar de centra i hjärnan som gör att vi kan sova och har vanligen effekt inom 30 minuter.
Angitt pris er maksimal utsalgspris fra apotek. Pakninger som selges uten resept er angitt med stjerne *. Det er fri prisfastsettelse for pakninger som selges uten resept, og maksimal utsalgspris kan derfor ikke angis.
Frequent Unwanted side effects incorporate headache, bitter style in the mouth, dry mouth and drowsiness. Major Unwanted side effects contain allergic reaction signs or symptoms which include swelling of your confront, lips, mouth or throat, which may lead to difficultly in swallowing or respiratory.
Han tok ten mg zopiklon da han gikk om bord i flyet. Ti timer senere våknet han opp i hotellsengen i New Orleans. Han husket ingenting fra turen.
In slumber laboratory studies of 1 to 21-working day duration in gentleman, zopiclone lowered sleep latency, enhanced the length of sleep and lessened the number of nocturnal awakenings. Zopiclone delayed the onset of REM rest but did not lessen consistently the total period of REM check here intervals. The duration of stage one slumber was shortened, and time spent in phase two sleep improved.
In case you have not instructed your doctor or pharmacist about any of the above mentioned, convey to them before you decide to take Imovane.
Notify your health practitioner or pharmacist When you are having any other medicines, such as any medicines, vitamins or supplements that you simply acquire with no prescription from your pharmacy, grocery store or wellness foods shop.
Right before having zopiclone, Allow your health practitioner know of some other remedies you might be having, together with any recognized allergy symptoms. Inform your doctor When you are pregnant or breastfeeding, as there have already been reports of Unintended effects and withdrawal indicators in infants subjected to the drug. [six]
Genotoxicity studies, using an ordinary battery of checks, showed no proof of gene mutations or chromosomal problems.
In case you have been addicted to alcohol or medication prior to now, it is necessary to tell your health care provider before starting Imovane.
Distribusjonsvolumet vil være ca. 5 liter hos et voksent menneske for et legemiddel som hovedsakelig befinner seg i plasma.